| Columbus to Odessa (Texas) | 1,215.64 mi (1,956.38 km) |
| Columbus to Ogden (Utah) | 1,515.66 mi (2,439.22 km) |
| Columbus to Oildale (California) | 1,981.59 mi (3,189.06 km) |
| Columbus to Ojus (Florida) | 982.95 mi (1,581.90 km) |
| Columbus to Okemos (Michigan) | 201.96 mi (325.03 km) |
| Columbus to Oklahoma City (Oklahoma) | 851.84 mi (1,370.90 km) |
| Columbus to Okmulgee (Oklahoma) | 771.46 mi (1,241.54 km) |
| Columbus to Olathe (Kansas) | 635.64 mi (1,022.96 km) |
| Columbus to Old Jamestown (Missouri) | 397.49 mi (639.70 km) |
| Columbus to Oldsmar (Florida) | 824.87 mi (1,327.49 km) |
| Columbus to Olean (New York) | 277.94 mi (447.31 km) |
| Columbus to Olive Branch (Mississippi) | 511.66 mi (823.44 km) |
| Columbus to Olivehurst (California) | 2,040.19 mi (3,283.36 km) |
| Columbus to Olney (Maryland) | 320.23 mi (515.36 km) |
| Columbus to Olympia (Washington) | 2,034.72 mi (3,274.57 km) |
