| Columbus to Clarksdale (Mississippi) | 578.28 mi (930.66 km) |
| Columbus to Clarkston (Georgia) | 432.20 mi (695.56 km) |
| Columbus to Clarksville (Indiana) | 188.23 mi (302.92 km) |
| Columbus to Clarksville (Tennessee) | 333.91 mi (537.38 km) |
| Columbus to Clawson (Michigan) | 176.43 mi (283.94 km) |
| Columbus to Clay (Alabama) | 478.51 mi (770.09 km) |
| Columbus to Clayton (California) | 2,080.37 mi (3,348.03 km) |
| Columbus to Clayton (Missouri) | 403.29 mi (649.03 km) |
| Columbus to Clayton (North Carolina) | 388.04 mi (624.49 km) |
| Columbus to Clayton (Ohio) | 71.65 mi (115.32 km) |
| Columbus to Clearfield (Utah) | 1,519.52 mi (2,445.43 km) |
| Columbus to Clearlake (California) | 2,098.22 mi (3,376.75 km) |
| Columbus to Clearwater (Florida) | 829.71 mi (1,335.30 km) |
| Columbus to Cleburne (Texas) | 960.17 mi (1,545.24 km) |
| Columbus to Clemmons (North Carolina) | 307.65 mi (495.11 km) |
