| Columbia to Security-Widefield (Colorado) | 1,359.46 mi (2,187.83 km) |
| Columbia to Sedalia (Missouri) | 757.14 mi (1,218.51 km) |
| Columbia to Sedro-Woolley (Washington) | 2,331.44 mi (3,752.08 km) |
| Columbia to Seguin (Texas) | 1,046.47 mi (1,684.12 km) |
| Columbia to Selden (New York) | 638.69 mi (1,027.88 km) |
| Columbia to Selma (Alabama) | 371.51 mi (597.88 km) |
| Columbia to Selma (California) | 2,175.09 mi (3,500.47 km) |
| Columbia to Selma (Texas) | 1,065.87 mi (1,715.35 km) |
| Columbia to Seminole (Florida) | 442.23 mi (711.69 km) |
| Columbia to Seven Hills (Ohio) | 509.05 mi (819.24 km) |
| Columbia to Seven Oaks (South Carolina) | 13.75 mi (22.13 km) |
| Columbia to Severn (Maryland) | 422.44 mi (679.85 km) |
| Columbia to Severna Park (Maryland) | 423.64 mi (681.79 km) |
| Columbia to Sevierville (Tennessee) | 197.69 mi (318.14 km) |
| Columbia to Seymour (Indiana) | 437.82 mi (704.61 km) |
