| Colonia to Santa Rosa (California) | 2,550.83 mi (4,105.16 km) |
| Colonia to Santaquin (Utah) | 1,960.89 mi (3,155.76 km) |
| Colonia to Santee (California) | 2,398.37 mi (3,859.80 km) |
| Colonia to Sapulpa (Oklahoma) | 1,219.43 mi (1,962.49 km) |
| Colonia to Saraland (Alabama) | 1,023.06 mi (1,646.46 km) |
| Colonia to Sarasota (Florida) | 1,028.82 mi (1,655.73 km) |
| Colonia to Sarasota Springs (Florida) | 1,028.93 mi (1,655.90 km) |
| Colonia to Saratoga (California) | 2,543.31 mi (4,093.06 km) |
| Colonia to Saratoga Springs (New York) | 173.21 mi (278.76 km) |
| Colonia to Saratoga Springs (Utah) | 1,961.20 mi (3,156.25 km) |
| Colonia to Sartell (Minnesota) | 1,059.15 mi (1,704.54 km) |
| Colonia to Satellite Beach (Florida) | 928.98 mi (1,495.04 km) |
| Colonia to Sauk Rapids (Minnesota) | 1,055.69 mi (1,698.97 km) |
| Colonia to Sault Ste. Marie (Michigan) | 646.68 mi (1,040.73 km) |
| Colonia to Savage (Minnesota) | 1,006.77 mi (1,620.24 km) |
