| Cohoes to Southern Pines (North Carolina) | 606.21 mi (975.60 km) |
| Cohoes to Southfield (Michigan) | 485.83 mi (781.86 km) |
| Cohoes to Southgate (Michigan) | 485.25 mi (780.94 km) |
| Cohoes to Southlake (Texas) | 1,440.63 mi (2,318.48 km) |
| Cohoes to Spanaway (Washington) | 2,362.48 mi (3,802.05 km) |
| Cohoes to Spanish Fork (Utah) | 1,956.71 mi (3,149.02 km) |
| Cohoes to Spanish Lake (Missouri) | 904.34 mi (1,455.40 km) |
| Cohoes to Spanish Springs (Nevada) | 2,368.94 mi (3,812.44 km) |
| Cohoes to Sparks (Nevada) | 2,373.28 mi (3,819.43 km) |
| Cohoes to Spartanburg (South Carolina) | 697.89 mi (1,123.14 km) |
| Cohoes to Spearfish (South Dakota) | 1,501.79 mi (2,416.89 km) |
| Cohoes to Speedway (Indiana) | 682.10 mi (1,097.73 km) |
| Cohoes to Spencer (Iowa) | 1,081.73 mi (1,740.88 km) |
| Cohoes to Spokane (Washington) | 2,125.78 mi (3,421.11 km) |
| Cohoes to Spokane Valley (Washington) | 2,116.66 mi (3,406.44 km) |
