| Cocoa to Southern Pines (North Carolina) | 477.32 mi (768.18 km) |
| Cocoa to Southfield (Michigan) | 983.77 mi (1,583.22 km) |
| Cocoa to Southgate (Michigan) | 964.78 mi (1,552.67 km) |
| Cocoa to Southlake (Texas) | 1,022.27 mi (1,645.18 km) |
| Cocoa to Spanaway (Washington) | 2,575.80 mi (4,145.35 km) |
| Cocoa to Spanish Fork (Utah) | 1,927.57 mi (3,102.13 km) |
| Cocoa to Spanish Lake (Missouri) | 900.08 mi (1,448.53 km) |
| Cocoa to Spanish Springs (Nevada) | 2,338.93 mi (3,764.14 km) |
| Cocoa to Sparks (Nevada) | 2,340.67 mi (3,766.94 km) |
| Cocoa to Spartanburg (South Carolina) | 458.47 mi (737.84 km) |
| Cocoa to Spearfish (South Dakota) | 1,686.31 mi (2,713.86 km) |
| Cocoa to Speedway (Indiana) | 848.08 mi (1,364.85 km) |
| Cocoa to Spencer (Iowa) | 1,296.45 mi (2,086.44 km) |
| Cocoa to Spokane (Washington) | 2,365.99 mi (3,807.70 km) |
| Cocoa to Spokane Valley (Washington) | 2,357.27 mi (3,793.65 km) |
