| Clute to Olympia Heights (Florida) | 950.91 mi (1,530.35 km) |
| Clute to Omaha (Nebraska) | 846.30 mi (1,362.00 km) |
| Clute to On Top of the World Designated Place (Florida) | 791.40 mi (1,273.64 km) |
| Clute to Onalaska (Wisconsin) | 1,052.59 mi (1,693.99 km) |
| Clute to Oneida (New York) | 1,462.15 mi (2,353.11 km) |
| Clute to Oneonta (New York) | 1,463.23 mi (2,354.84 km) |
| Clute to Ontario (California) | 1,349.96 mi (2,172.55 km) |
| Clute to Ontario (Oregon) | 1,575.35 mi (2,535.29 km) |
| Clute to Opa-locka (Florida) | 952.37 mi (1,532.69 km) |
| Clute to Opelika (Alabama) | 644.96 mi (1,037.96 km) |
| Clute to Opelousas (Louisiana) | 224.22 mi (360.84 km) |
| Clute to Orange (California) | 1,359.81 mi (2,188.40 km) |
| Clute to Orange (Texas) | 124.17 mi (199.83 km) |
| Clute to Orange City (Florida) | 852.31 mi (1,371.67 km) |
| Clute to Orangeburg (South Carolina) | 911.01 mi (1,466.12 km) |
