| Clemson to University Place (Washington) | 2,217.57 mi (3,568.83 km) |
| Clemson to Upland (California) | 1,977.02 mi (3,181.70 km) |
| Clemson to Upper Arlington (Ohio) | 369.47 mi (594.61 km) |
| Clemson to Upper Grand Lagoon (Florida) | 355.58 mi (572.24 km) |
| Clemson to Upper Montclair (New Jersey) | 633.75 mi (1,019.92 km) |
| Clemson to Urbana (Illinois) | 477.25 mi (768.06 km) |
| Clemson to Urbana (Maryland) | 440.32 mi (708.62 km) |
| Clemson to Urbana (Ohio) | 378.36 mi (608.91 km) |
| Clemson to Urbandale (Iowa) | 764.44 mi (1,230.25 km) |
| Clemson to Utica (New York) | 709.45 mi (1,141.75 km) |
| Clemson to Uvalde (Texas) | 1,062.27 mi (1,709.56 km) |
| Clemson to Vacaville (California) | 2,172.59 mi (3,496.45 km) |
| Clemson to Vadnais Heights (Minnesota) | 898.34 mi (1,445.74 km) |
| Clemson to Vail (Arizona) | 1,614.44 mi (2,598.18 km) |
| Clemson to Valdosta (Georgia) | 266.25 mi (428.49 km) |
