| Clemson to Superior (Colorado) | 1,276.61 mi (2,054.51 km) |
| Clemson to Superior (Wisconsin) | 959.94 mi (1,544.88 km) |
| Clemson to Surprise (Arizona) | 1,689.40 mi (2,718.82 km) |
| Clemson to Susanville (California) | 2,091.78 mi (3,366.40 km) |
| Clemson to Sussex (Wisconsin) | 651.97 mi (1,049.25 km) |
| Clemson to Suwanee (Georgia) | 83.93 mi (135.08 km) |
| Clemson to Swansea (Illinois) | 478.97 mi (770.82 km) |
| Clemson to Sweetwater (Florida) | 632.18 mi (1,017.39 km) |
| Clemson to Sweetwater (Texas) | 1,023.09 mi (1,646.51 km) |
| Clemson to Sycamore (Illinois) | 596.65 mi (960.22 km) |
| Clemson to Sylacauga (Alabama) | 223.36 mi (359.46 km) |
| Clemson to Sylvania (Ohio) | 487.90 mi (785.20 km) |
| Clemson to Syosset (New York) | 661.30 mi (1,064.26 km) |
| Clemson to Syracuse (New York) | 679.26 mi (1,093.16 km) |
| Clemson to Syracuse (Utah) | 1,646.98 mi (2,650.56 km) |
