| Clemson to Storm Lake (Iowa) | 863.72 mi (1,390.02 km) |
| Clemson to Storrs (Connecticut) | 754.43 mi (1,214.14 km) |
| Clemson to Stoughton (Wisconsin) | 665.29 mi (1,070.68 km) |
| Clemson to Stow (Ohio) | 454.83 mi (731.98 km) |
| Clemson to Streamwood (Illinois) | 584.09 mi (940.00 km) |
| Clemson to Streator (Illinois) | 552.54 mi (889.22 km) |
| Clemson to Streetsboro (Ohio) | 459.94 mi (740.20 km) |
| Clemson to Strongsville (Ohio) | 461.12 mi (742.10 km) |
| Clemson to Stuart (Florida) | 539.21 mi (867.78 km) |
| Clemson to Stuarts Draft (Virginia) | 311.83 mi (501.84 km) |
| Clemson to Sturgis (Michigan) | 511.49 mi (823.16 km) |
| Clemson to Suamico (Wisconsin) | 741.84 mi (1,193.87 km) |
| Clemson to Sudley (Virginia) | 408.59 mi (657.56 km) |
| Clemson to Suffern (New York) | 648.09 mi (1,042.99 km) |
| Clemson to Suffolk (Virginia) | 373.14 mi (600.51 km) |
