| Clemson to Silver Firs (Washington) | 2,206.39 mi (3,550.84 km) |
| Clemson to Silver Spring (Maryland) | 437.55 mi (704.17 km) |
| Clemson to Silver Springs Shores (Florida) | 387.75 mi (624.03 km) |
| Clemson to Silverdale (Washington) | 2,228.59 mi (3,586.58 km) |
| Clemson to Silverton (Oregon) | 2,211.33 mi (3,558.78 km) |
| Clemson to Simi Valley (California) | 2,036.07 mi (3,276.73 km) |
| Clemson to Simpsonville (South Carolina) | 31.71 mi (51.02 km) |
| Clemson to Sioux City (Iowa) | 908.64 mi (1,462.32 km) |
| Clemson to Sioux Falls (South Dakota) | 962.70 mi (1,549.32 km) |
| Clemson to Skokie (Illinois) | 573.61 mi (923.14 km) |
| Clemson to Sleepy Hollow (New York) | 657.96 mi (1,058.89 km) |
| Clemson to Slidell (Louisiana) | 506.96 mi (815.88 km) |
| Clemson to Smithfield (North Carolina) | 258.69 mi (416.32 km) |
| Clemson to Smithfield (Utah) | 1,640.78 mi (2,640.58 km) |
| Clemson to Smithville (Missouri) | 724.91 mi (1,166.62 km) |
