| Clemson to Santa Rosa (California) | 2,211.84 mi (3,559.61 km) |
| Clemson to Santaquin (Utah) | 1,625.98 mi (2,616.76 km) |
| Clemson to Santee (California) | 1,957.42 mi (3,150.17 km) |
| Clemson to Sapulpa (Oklahoma) | 753.85 mi (1,213.20 km) |
| Clemson to Saraland (Alabama) | 405.63 mi (652.79 km) |
| Clemson to Sarasota (Florida) | 507.74 mi (817.13 km) |
| Clemson to Sarasota Springs (Florida) | 509.95 mi (820.69 km) |
| Clemson to Saratoga (California) | 2,184.26 mi (3,515.22 km) |
| Clemson to Saratoga Springs (New York) | 755.17 mi (1,215.33 km) |
| Clemson to Saratoga Springs (Utah) | 1,634.23 mi (2,630.03 km) |
| Clemson to Sartell (Minnesota) | 964.29 mi (1,551.88 km) |
| Clemson to Satellite Beach (Florida) | 467.96 mi (753.10 km) |
| Clemson to Sauk Rapids (Minnesota) | 961.06 mi (1,546.68 km) |
| Clemson to Sault Ste. Marie (Michigan) | 819.22 mi (1,318.40 km) |
| Clemson to Savage (Minnesota) | 892.04 mi (1,435.60 km) |
