| Clemson to Oswego (Illinois) | 568.84 mi (915.47 km) |
| Clemson to Oswego (New York) | 693.49 mi (1,116.07 km) |
| Clemson to Otsego (Minnesota) | 926.70 mi (1,491.38 km) |
| Clemson to Ottawa (Illinois) | 565.04 mi (909.34 km) |
| Clemson to Ottawa (Kansas) | 740.63 mi (1,191.93 km) |
| Clemson to Ottumwa (Iowa) | 682.10 mi (1,097.74 km) |
| Clemson to Overland (Missouri) | 501.87 mi (807.68 km) |
| Clemson to Overland Park (Kansas) | 717.66 mi (1,154.96 km) |
| Clemson to Overlea (Maryland) | 474.27 mi (763.27 km) |
| Clemson to Oviedo (Florida) | 427.14 mi (687.42 km) |
| Clemson to Owasso (Oklahoma) | 740.18 mi (1,191.21 km) |
| Clemson to Owatonna (Minnesota) | 854.16 mi (1,374.64 km) |
| Clemson to Owensboro (Kentucky) | 320.37 mi (515.59 km) |
| Clemson to Owings Mills (Maryland) | 465.56 mi (749.25 km) |
| Clemson to Owosso (Michigan) | 578.94 mi (931.71 km) |
