| Clemson to Orangevale (California) | 2,130.38 mi (3,428.52 km) |
| Clemson to Orchards (Washington) | 2,203.64 mi (3,546.41 km) |
| Clemson to Orcutt (California) | 2,121.66 mi (3,414.48 km) |
| Clemson to Oregon (Ohio) | 482.66 mi (776.77 km) |
| Clemson to Oregon (Wisconsin) | 670.05 mi (1,078.35 km) |
| Clemson to Oregon City (Oregon) | 2,204.24 mi (3,547.38 km) |
| Clemson to Orem (Utah) | 1,622.63 mi (2,611.37 km) |
| Clemson to Orinda (California) | 2,187.48 mi (3,520.41 km) |
| Clemson to Orland Park (Illinois) | 551.23 mi (887.13 km) |
| Clemson to Orlando (Florida) | 437.51 mi (704.10 km) |
| Clemson to Ormond Beach (Florida) | 385.33 mi (620.13 km) |
| Clemson to Oro Valley (Arizona) | 1,623.96 mi (2,613.51 km) |
| Clemson to Oroville (California) | 2,144.74 mi (3,451.63 km) |
| Clemson to Oshkosh (Wisconsin) | 714.18 mi (1,149.37 km) |
| Clemson to Oskaloosa (Iowa) | 702.67 mi (1,130.84 km) |
