| Clemson to Odessa (Texas) | 1,142.82 mi (1,839.20 km) |
| Clemson to Ogden (Utah) | 1,642.79 mi (2,643.82 km) |
| Clemson to Oildale (California) | 2,037.53 mi (3,279.09 km) |
| Clemson to Ojus (Florida) | 623.32 mi (1,003.14 km) |
| Clemson to Okemos (Michigan) | 560.92 mi (902.71 km) |
| Clemson to Oklahoma City (Oklahoma) | 832.28 mi (1,339.42 km) |
| Clemson to Okmulgee (Oklahoma) | 747.61 mi (1,203.17 km) |
| Clemson to Olathe (Kansas) | 724.29 mi (1,165.64 km) |
| Clemson to Old Jamestown (Missouri) | 503.22 mi (809.86 km) |
| Clemson to Oldsmar (Florida) | 458.38 mi (737.69 km) |
| Clemson to Olean (New York) | 563.33 mi (906.59 km) |
| Clemson to Olive Branch (Mississippi) | 399.38 mi (642.74 km) |
| Clemson to Olivehurst (California) | 2,146.31 mi (3,454.16 km) |
| Clemson to Olney (Maryland) | 442.14 mi (711.56 km) |
| Clemson to Olympia (Washington) | 2,232.16 mi (3,592.31 km) |
