| Clemson to Emeryville (California) | 2,194.01 mi (3,530.91 km) |
| Clemson to Emmaus (Pennsylvania) | 568.58 mi (915.04 km) |
| Clemson to Emporia (Kansas) | 785.07 mi (1,263.45 km) |
| Clemson to Encinitas (California) | 1,969.96 mi (3,170.34 km) |
| Clemson to Endicott (New York) | 628.80 mi (1,011.96 km) |
| Clemson to Endwell (New York) | 631.24 mi (1,015.88 km) |
| Clemson to Englewood (Colorado) | 1,264.85 mi (2,035.58 km) |
| Clemson to Englewood (Florida) | 533.54 mi (858.66 km) |
| Clemson to Englewood (New Jersey) | 645.06 mi (1,038.12 km) |
| Clemson to Englewood (Ohio) | 367.24 mi (591.01 km) |
| Clemson to Enid (Oklahoma) | 853.94 mi (1,374.29 km) |
| Clemson to Ennis (Texas) | 812.14 mi (1,307.01 km) |
| Clemson to Ensley (Florida) | 387.13 mi (623.02 km) |
| Clemson to Enterprise (Alabama) | 290.95 mi (468.25 km) |
| Clemson to Enterprise (Nevada) | 1,820.73 mi (2,930.18 km) |
