| Clemson to Desert Hot Springs (California) | 1,916.42 mi (3,084.17 km) |
| Clemson to DeSoto (Texas) | 820.25 mi (1,320.06 km) |
| Clemson to Destin (Florida) | 364.89 mi (587.23 km) |
| Clemson to Destrehan (Louisiana) | 548.34 mi (882.46 km) |
| Clemson to Detroit (Michigan) | 532.23 mi (856.54 km) |
| Clemson to Diamond Bar (California) | 1,987.36 mi (3,198.35 km) |
| Clemson to Diamond Springs (California) | 2,109.83 mi (3,395.45 km) |
| Clemson to Dickinson (North Dakota) | 1,336.35 mi (2,150.64 km) |
| Clemson to Dickinson (Texas) | 802.08 mi (1,290.82 km) |
| Clemson to Dickson (Tennessee) | 273.68 mi (440.44 km) |
| Clemson to Difficult Run (Virginia) | 419.81 mi (675.62 km) |
| Clemson to Dinuba (California) | 2,046.71 mi (3,293.86 km) |
| Clemson to Discovery Bay (California) | 2,155.86 mi (3,469.51 km) |
| Clemson to Dix Hills (New York) | 667.70 mi (1,074.56 km) |
| Clemson to Dixon (California) | 2,164.34 mi (3,483.17 km) |
