| Cincinnati to Southern Pines (North Carolina) | 391.46 mi (630.00 km) |
| Cincinnati to Southfield (Michigan) | 239.46 mi (385.37 km) |
| Cincinnati to Southgate (Michigan) | 222.35 mi (357.84 km) |
| Cincinnati to Southlake (Texas) | 824.44 mi (1,326.81 km) |
| Cincinnati to Spanaway (Washington) | 1,968.34 mi (3,167.74 km) |
| Cincinnati to Spanish Fork (Utah) | 1,439.98 mi (2,317.42 km) |
| Cincinnati to Spanish Lake (Missouri) | 307.23 mi (494.43 km) |
| Cincinnati to Spanish Springs (Nevada) | 1,865.63 mi (3,002.44 km) |
| Cincinnati to Sparks (Nevada) | 1,869.11 mi (3,008.04 km) |
| Cincinnati to Spartanburg (South Carolina) | 323.00 mi (519.82 km) |
| Cincinnati to Spearfish (South Dakota) | 1,057.68 mi (1,702.18 km) |
| Cincinnati to Speedway (Indiana) | 103.28 mi (166.21 km) |
| Cincinnati to Spencer (Iowa) | 618.64 mi (995.60 km) |
| Cincinnati to Spokane (Washington) | 1,739.11 mi (2,798.82 km) |
| Cincinnati to Spokane Valley (Washington) | 1,729.91 mi (2,784.03 km) |
