| Chicago Heights to Southern Pines (North Carolina) | 623.45 mi (1,003.35 km) |
| Chicago Heights to Southfield (Michigan) | 234.30 mi (377.06 km) |
| Chicago Heights to Southgate (Michigan) | 232.88 mi (374.79 km) |
| Chicago Heights to Southlake (Texas) | 788.57 mi (1,269.07 km) |
| Chicago Heights to Spanaway (Washington) | 1,747.60 mi (2,812.50 km) |
| Chicago Heights to Spanish Fork (Utah) | 1,255.08 mi (2,019.85 km) |
| Chicago Heights to Spanish Lake (Missouri) | 231.98 mi (373.34 km) |
| Chicago Heights to Spanish Springs (Nevada) | 1,676.23 mi (2,697.63 km) |
| Chicago Heights to Sparks (Nevada) | 1,680.11 mi (2,703.87 km) |
| Chicago Heights to Spartanburg (South Carolina) | 549.09 mi (883.68 km) |
| Chicago Heights to Spearfish (South Dakota) | 841.63 mi (1,354.48 km) |
| Chicago Heights to Speedway (Indiana) | 139.08 mi (223.82 km) |
| Chicago Heights to Spencer (Iowa) | 400.21 mi (644.08 km) |
| Chicago Heights to Spokane (Washington) | 1,516.15 mi (2,440.01 km) |
| Chicago Heights to Spokane Valley (Washington) | 1,506.93 mi (2,425.17 km) |
