| Chicago to Spout Springs (North Carolina) | 650.78 mi (1,047.33 km) |
| Chicago to Spring (Texas) | 919.55 mi (1,479.87 km) |
| Chicago to Spring Creek (Nevada) | 1,444.60 mi (2,324.86 km) |
| Chicago to Spring Hill (Florida) | 967.30 mi (1,556.71 km) |
| Chicago to Spring Hill (Tennessee) | 423.10 mi (680.91 km) |
| Chicago to Spring Lake (North Carolina) | 656.65 mi (1,056.77 km) |
| Chicago to Spring Valley (California) | 1,718.27 mi (2,765.29 km) |
| Chicago to Spring Valley (Nevada) | 1,526.36 mi (2,456.44 km) |
| Chicago to Spring Valley (New York) | 707.01 mi (1,137.82 km) |
| Chicago to Springboro (Ohio) | 239.59 mi (385.59 km) |
| Chicago to Springdale (Arkansas) | 522.10 mi (840.24 km) |
| Chicago to Springdale (New Jersey) | 677.41 mi (1,090.19 km) |
| Chicago to Springdale (Ohio) | 243.60 mi (392.03 km) |
| Chicago to Springfield (Illinois) | 175.99 mi (283.22 km) |
| Chicago to Springfield (Massachusetts) | 777.25 mi (1,250.87 km) |
