| Chicago to Smyrna (Delaware) | 657.24 mi (1,057.72 km) |
| Chicago to Smyrna (Georgia) | 577.35 mi (929.15 km) |
| Chicago to Smyrna (Tennessee) | 410.25 mi (660.24 km) |
| Chicago to Snellville (Georgia) | 586.76 mi (944.30 km) |
| Chicago to Snoqualmie (Washington) | 1,708.53 mi (2,749.61 km) |
| Chicago to Snyder (Texas) | 960.31 mi (1,545.47 km) |
| Chicago to Socastee (South Carolina) | 735.25 mi (1,183.27 km) |
| Chicago to Socorro (Texas) | 1,242.35 mi (1,999.36 km) |
| Chicago to Soddy-Daisy (Tennessee) | 474.44 mi (763.54 km) |
| Chicago to Solana Beach (California) | 1,723.47 mi (2,773.66 km) |
| Chicago to Soledad (California) | 1,829.42 mi (2,944.17 km) |
| Chicago to Solon (Ohio) | 324.12 mi (521.61 km) |
| Chicago to Somers Point (New Jersey) | 707.39 mi (1,138.43 km) |
| Chicago to Somerset (Kentucky) | 367.11 mi (590.80 km) |
| Chicago to Somerset (New Jersey) | 691.18 mi (1,112.35 km) |
