| Chesapeake to Southern Pines (North Carolina) | 201.57 mi (324.39 km) |
| Chesapeake to Southfield (Michigan) | 545.35 mi (877.66 km) |
| Chesapeake to Southgate (Michigan) | 530.22 mi (853.30 km) |
| Chesapeake to Southlake (Texas) | 1,207.66 mi (1,943.54 km) |
| Chesapeake to Spanaway (Washington) | 2,440.13 mi (3,927.00 km) |
| Chesapeake to Spanish Fork (Utah) | 1,915.60 mi (3,082.86 km) |
| Chesapeake to Spanish Lake (Missouri) | 772.90 mi (1,243.87 km) |
| Chesapeake to Spanish Springs (Nevada) | 2,341.88 mi (3,768.90 km) |
| Chesapeake to Sparks (Nevada) | 2,345.25 mi (3,774.31 km) |
| Chesapeake to Spartanburg (South Carolina) | 336.99 mi (542.33 km) |
| Chesapeake to Spearfish (South Dakota) | 1,532.38 mi (2,466.13 km) |
| Chesapeake to Speedway (Indiana) | 580.70 mi (934.54 km) |
| Chesapeake to Spencer (Iowa) | 1,091.26 mi (1,756.21 km) |
| Chesapeake to Spokane (Washington) | 2,208.57 mi (3,554.34 km) |
| Chesapeake to Spokane Valley (Washington) | 2,199.34 mi (3,539.50 km) |
