| Charlotte to Storm Lake (Iowa) | 925.44 mi (1,489.35 km) |
| Charlotte to Storrs (Connecticut) | 649.80 mi (1,045.76 km) |
| Charlotte to Stoughton (Wisconsin) | 697.00 mi (1,121.71 km) |
| Charlotte to Stow (Ohio) | 413.66 mi (665.72 km) |
| Charlotte to Streamwood (Illinois) | 615.05 mi (989.83 km) |
| Charlotte to Streator (Illinois) | 596.09 mi (959.32 km) |
| Charlotte to Streetsboro (Ohio) | 417.66 mi (672.15 km) |
| Charlotte to Strongsville (Ohio) | 425.25 mi (684.38 km) |
| Charlotte to Stuart (Florida) | 554.68 mi (892.67 km) |
| Charlotte to Stuarts Draft (Virginia) | 218.20 mi (351.16 km) |
| Charlotte to Sturgis (Michigan) | 518.37 mi (834.23 km) |
| Charlotte to Suamico (Wisconsin) | 755.14 mi (1,215.29 km) |
| Charlotte to Sudley (Virginia) | 308.20 mi (495.99 km) |
| Charlotte to Suffern (New York) | 546.00 mi (878.70 km) |
| Charlotte to Suffolk (Virginia) | 255.88 mi (411.80 km) |
