| Charlotte to St. Simons (Georgia) | 280.34 mi (451.17 km) |
| Charlotte to Stafford (Texas) | 940.68 mi (1,513.87 km) |
| Charlotte to Stallings (North Carolina) | 11.83 mi (19.04 km) |
| Charlotte to Stamford (Connecticut) | 567.05 mi (912.58 km) |
| Charlotte to Stanford (California) | 2,288.01 mi (3,682.20 km) |
| Charlotte to Stanton (California) | 2,105.91 mi (3,389.14 km) |
| Charlotte to Star (Idaho) | 1,973.73 mi (3,176.41 km) |
| Charlotte to Starkville (Mississippi) | 471.95 mi (759.52 km) |
| Charlotte to State College (Pennsylvania) | 418.25 mi (673.11 km) |
| Charlotte to Staten Island (New York) | 519.88 mi (836.67 km) |
| Charlotte to Statesboro (Georgia) | 198.97 mi (320.22 km) |
| Charlotte to Statesville (North Carolina) | 39.86 mi (64.14 km) |
| Charlotte to Staunton (Virginia) | 226.22 mi (364.07 km) |
| Charlotte to Steamboat Springs (Colorado) | 1,458.43 mi (2,347.12 km) |
| Charlotte to Steiner Ranch (Texas) | 1,044.58 mi (1,681.09 km) |
