| Charlotte to Silver Firs (Washington) | 2,275.97 mi (3,662.82 km) |
| Charlotte to Silver Spring (Maryland) | 335.79 mi (540.40 km) |
| Charlotte to Silver Springs Shores (Florida) | 426.82 mi (686.90 km) |
| Charlotte to Silverdale (Washington) | 2,298.94 mi (3,699.78 km) |
| Charlotte to Silverton (Oregon) | 2,289.53 mi (3,684.65 km) |
| Charlotte to Simi Valley (California) | 2,140.80 mi (3,445.28 km) |
| Charlotte to Simpsonville (South Carolina) | 87.31 mi (140.50 km) |
| Charlotte to Sioux City (Iowa) | 974.69 mi (1,568.60 km) |
| Charlotte to Sioux Falls (South Dakota) | 1,023.18 mi (1,646.66 km) |
| Charlotte to Skokie (Illinois) | 600.94 mi (967.11 km) |
| Charlotte to Sleepy Hollow (New York) | 554.85 mi (892.94 km) |
| Charlotte to Slidell (Louisiana) | 621.01 mi (999.42 km) |
| Charlotte to Smithfield (North Carolina) | 141.36 mi (227.50 km) |
| Charlotte to Smithfield (Utah) | 1,726.58 mi (2,778.66 km) |
| Charlotte to Smithville (Missouri) | 807.78 mi (1,299.99 km) |
