| Charlotte to Seymour (Tennessee) | 171.45 mi (275.93 km) |
| Charlotte to Shady Hills (Florida) | 480.77 mi (773.73 km) |
| Charlotte to Shafter (California) | 2,148.72 mi (3,458.03 km) |
| Charlotte to Shaker Heights (Ohio) | 434.69 mi (699.57 km) |
| Charlotte to Shakopee (Minnesota) | 938.65 mi (1,510.60 km) |
| Charlotte to Sharon (Pennsylvania) | 416.72 mi (670.65 km) |
| Charlotte to Sharonville (Ohio) | 343.36 mi (552.58 km) |
| Charlotte to Shasta Lake (California) | 2,273.68 mi (3,659.13 km) |
| Charlotte to Shawnee (Kansas) | 812.80 mi (1,308.08 km) |
| Charlotte to Shawnee (Oklahoma) | 909.08 mi (1,463.02 km) |
| Charlotte to Sheboygan (Wisconsin) | 694.38 mi (1,117.50 km) |
| Charlotte to Shelby (North Carolina) | 40.73 mi (65.55 km) |
| Charlotte to Shelbyville (Indiana) | 403.87 mi (649.96 km) |
| Charlotte to Shelbyville (Kentucky) | 319.76 mi (514.60 km) |
| Charlotte to Shelbyville (Tennessee) | 317.37 mi (510.76 km) |
