| Charlotte to Santa Rosa (California) | 2,306.91 mi (3,712.61 km) |
| Charlotte to Santaquin (Utah) | 1,717.89 mi (2,764.68 km) |
| Charlotte to Santee (California) | 2,065.22 mi (3,323.66 km) |
| Charlotte to Sapulpa (Oklahoma) | 858.67 mi (1,381.90 km) |
| Charlotte to Saraland (Alabama) | 517.55 mi (832.92 km) |
| Charlotte to Sarasota (Florida) | 553.03 mi (890.02 km) |
| Charlotte to Sarasota Springs (Florida) | 554.35 mi (892.15 km) |
| Charlotte to Saratoga (California) | 2,282.06 mi (3,672.62 km) |
| Charlotte to Saratoga Springs (New York) | 661.04 mi (1,063.85 km) |
| Charlotte to Saratoga Springs (Utah) | 1,724.96 mi (2,776.06 km) |
| Charlotte to Sartell (Minnesota) | 1,004.14 mi (1,616.01 km) |
| Charlotte to Satellite Beach (Florida) | 485.92 mi (782.01 km) |
| Charlotte to Sauk Rapids (Minnesota) | 1,000.77 mi (1,610.58 km) |
| Charlotte to Sault Ste. Marie (Michigan) | 800.39 mi (1,288.10 km) |
| Charlotte to Savage (Minnesota) | 933.50 mi (1,502.32 km) |
