| Charlotte to Desert Hot Springs (California) | 2,022.43 mi (3,254.79 km) |
| Charlotte to DeSoto (Texas) | 935.83 mi (1,506.07 km) |
| Charlotte to Destin (Florida) | 466.60 mi (750.92 km) |
| Charlotte to Destrehan (Louisiana) | 662.54 mi (1,066.26 km) |
| Charlotte to Detroit (Michigan) | 510.57 mi (821.68 km) |
| Charlotte to Diamond Bar (California) | 2,092.88 mi (3,368.17 km) |
| Charlotte to Diamond Springs (California) | 2,204.70 mi (3,548.12 km) |
| Charlotte to Dickinson (North Dakota) | 1,392.61 mi (2,241.18 km) |
| Charlotte to Dickinson (Texas) | 919.66 mi (1,480.05 km) |
| Charlotte to Dickson (Tennessee) | 371.69 mi (598.18 km) |
| Charlotte to Difficult Run (Virginia) | 319.32 mi (513.90 km) |
| Charlotte to Dinuba (California) | 2,146.71 mi (3,454.79 km) |
| Charlotte to Discovery Bay (California) | 2,252.37 mi (3,624.84 km) |
| Charlotte to Dix Hills (New York) | 561.59 mi (903.78 km) |
| Charlotte to Dixon (California) | 2,259.59 mi (3,636.46 km) |
