| Chapel Hill to St. Simons (Georgia) | 354.86 mi (571.09 km) |
| Chapel Hill to Stafford (Texas) | 1,052.24 mi (1,693.42 km) |
| Chapel Hill to Stallings (North Carolina) | 107.25 mi (172.61 km) |
| Chapel Hill to Stamford (Connecticut) | 464.25 mi (747.13 km) |
| Chapel Hill to Stanford (California) | 2,371.18 mi (3,816.05 km) |
| Chapel Hill to Stanton (California) | 2,198.69 mi (3,538.45 km) |
| Chapel Hill to Star (Idaho) | 2,040.07 mi (3,283.17 km) |
| Chapel Hill to Starkville (Mississippi) | 581.40 mi (935.67 km) |
| Chapel Hill to State College (Pennsylvania) | 342.10 mi (550.55 km) |
| Chapel Hill to Staten Island (New York) | 416.84 mi (670.83 km) |
| Chapel Hill to Statesboro (Georgia) | 287.35 mi (462.44 km) |
| Chapel Hill to Statesville (North Carolina) | 103.08 mi (165.88 km) |
| Chapel Hill to Staunton (Virginia) | 154.23 mi (248.22 km) |
| Chapel Hill to Steamboat Springs (Colorado) | 1,534.31 mi (2,469.23 km) |
| Chapel Hill to Steiner Ranch (Texas) | 1,154.26 mi (1,857.60 km) |
