| Chapel Hill to Smyrna (Delaware) | 298.88 mi (481.01 km) |
| Chapel Hill to Smyrna (Georgia) | 341.53 mi (549.65 km) |
| Chapel Hill to Smyrna (Tennessee) | 418.71 mi (673.84 km) |
| Chapel Hill to Snellville (Georgia) | 315.60 mi (507.90 km) |
| Chapel Hill to Snoqualmie (Washington) | 2,314.04 mi (3,724.09 km) |
| Chapel Hill to Snyder (Texas) | 1,264.95 mi (2,035.74 km) |
| Chapel Hill to Socastee (South Carolina) | 154.78 mi (249.09 km) |
| Chapel Hill to Socorro (Texas) | 1,585.68 mi (2,551.91 km) |
| Chapel Hill to Soddy-Daisy (Tennessee) | 347.72 mi (559.60 km) |
| Chapel Hill to Solana Beach (California) | 2,172.83 mi (3,496.83 km) |
| Chapel Hill to Soledad (California) | 2,340.04 mi (3,765.93 km) |
| Chapel Hill to Solon (Ohio) | 398.78 mi (641.78 km) |
| Chapel Hill to Somers Point (New Jersey) | 337.09 mi (542.50 km) |
| Chapel Hill to Somerset (Kentucky) | 319.53 mi (514.24 km) |
| Chapel Hill to Somerset (New Jersey) | 400.97 mi (645.29 km) |
