| Chapel Hill to Silver Firs (Washington) | 2,330.15 mi (3,750.02 km) |
| Chapel Hill to Silver Spring (Maryland) | 239.59 mi (385.59 km) |
| Chapel Hill to Silver Springs Shores (Florida) | 501.66 mi (807.34 km) |
| Chapel Hill to Silverdale (Washington) | 2,353.83 mi (3,788.13 km) |
| Chapel Hill to Silverton (Oregon) | 2,352.45 mi (3,785.90 km) |
| Chapel Hill to Simi Valley (California) | 2,232.28 mi (3,592.51 km) |
| Chapel Hill to Simpsonville (South Carolina) | 199.38 mi (320.87 km) |
| Chapel Hill to Sioux City (Iowa) | 1,031.18 mi (1,659.52 km) |
| Chapel Hill to Sioux Falls (South Dakota) | 1,074.00 mi (1,728.44 km) |
| Chapel Hill to Skokie (Illinois) | 629.10 mi (1,012.44 km) |
| Chapel Hill to Sleepy Hollow (New York) | 453.09 mi (729.18 km) |
| Chapel Hill to Slidell (Louisiana) | 733.04 mi (1,179.72 km) |
| Chapel Hill to Smithfield (North Carolina) | 48.10 mi (77.41 km) |
| Chapel Hill to Smithfield (Utah) | 1,798.45 mi (2,894.33 km) |
| Chapel Hill to Smithville (Missouri) | 881.56 mi (1,418.73 km) |
