| Chapel Hill to Seymour (Tennessee) | 264.59 mi (425.82 km) |
| Chapel Hill to Shady Hills (Florida) | 558.68 mi (899.11 km) |
| Chapel Hill to Shafter (California) | 2,237.39 mi (3,600.73 km) |
| Chapel Hill to Shaker Heights (Ohio) | 406.43 mi (654.09 km) |
| Chapel Hill to Shakopee (Minnesota) | 973.00 mi (1,565.89 km) |
| Chapel Hill to Sharon (Pennsylvania) | 375.05 mi (603.58 km) |
| Chapel Hill to Sharonville (Ohio) | 374.16 mi (602.15 km) |
| Chapel Hill to Shasta Lake (California) | 2,348.70 mi (3,779.86 km) |
| Chapel Hill to Shawnee (Kansas) | 889.37 mi (1,431.30 km) |
| Chapel Hill to Shawnee (Oklahoma) | 1,005.92 mi (1,618.87 km) |
| Chapel Hill to Sheboygan (Wisconsin) | 709.19 mi (1,141.33 km) |
| Chapel Hill to Shelby (North Carolina) | 147.48 mi (237.35 km) |
| Chapel Hill to Shelbyville (Indiana) | 444.55 mi (715.43 km) |
| Chapel Hill to Shelbyville (Kentucky) | 375.75 mi (604.72 km) |
| Chapel Hill to Shelbyville (Tennessee) | 416.80 mi (670.78 km) |
