| Chapel Hill to Security-Widefield (Colorado) | 1,419.11 mi (2,283.84 km) |
| Chapel Hill to Sedalia (Missouri) | 802.37 mi (1,291.29 km) |
| Chapel Hill to Sedro-Woolley (Washington) | 2,337.89 mi (3,762.47 km) |
| Chapel Hill to Seguin (Texas) | 1,181.27 mi (1,901.07 km) |
| Chapel Hill to Selden (New York) | 470.92 mi (757.88 km) |
| Chapel Hill to Selma (Alabama) | 517.13 mi (832.24 km) |
| Chapel Hill to Selma (California) | 2,244.25 mi (3,611.76 km) |
| Chapel Hill to Selma (Texas) | 1,199.92 mi (1,931.09 km) |
| Chapel Hill to Seminole (Florida) | 600.03 mi (965.66 km) |
| Chapel Hill to Seven Hills (Ohio) | 402.65 mi (648.00 km) |
| Chapel Hill to Seven Oaks (South Carolina) | 176.22 mi (283.59 km) |
| Chapel Hill to Severn (Maryland) | 256.16 mi (412.25 km) |
| Chapel Hill to Severna Park (Maryland) | 256.88 mi (413.41 km) |
| Chapel Hill to Sevierville (Tennessee) | 253.43 mi (407.86 km) |
| Chapel Hill to Seymour (Indiana) | 429.78 mi (691.66 km) |
