| Chapel Hill to Santa Rosa (California) | 2,387.49 mi (3,842.30 km) |
| Chapel Hill to Santaquin (Utah) | 1,796.07 mi (2,890.50 km) |
| Chapel Hill to Santee (California) | 2,160.36 mi (3,476.77 km) |
| Chapel Hill to Sapulpa (Oklahoma) | 952.86 mi (1,533.48 km) |
| Chapel Hill to Saraland (Alabama) | 629.16 mi (1,012.54 km) |
| Chapel Hill to Sarasota (Florida) | 628.05 mi (1,010.74 km) |
| Chapel Hill to Sarasota Springs (Florida) | 628.71 mi (1,011.82 km) |
| Chapel Hill to Saratoga (California) | 2,365.64 mi (3,807.13 km) |
| Chapel Hill to Saratoga Springs (New York) | 567.23 mi (912.88 km) |
| Chapel Hill to Saratoga Springs (Utah) | 1,801.91 mi (2,899.90 km) |
| Chapel Hill to Sartell (Minnesota) | 1,035.84 mi (1,667.03 km) |
| Chapel Hill to Satellite Beach (Florida) | 543.14 mi (874.09 km) |
| Chapel Hill to Sauk Rapids (Minnesota) | 1,032.38 mi (1,661.45 km) |
| Chapel Hill to Sault Ste. Marie (Michigan) | 779.70 mi (1,254.80 km) |
| Chapel Hill to Savage (Minnesota) | 967.59 mi (1,557.19 km) |
