| Chapel Hill to Sanford (Maine) | 679.20 mi (1,093.07 km) |
| Chapel Hill to Sanford (North Carolina) | 31.34 mi (50.44 km) |
| Chapel Hill to Sanger (California) | 2,239.45 mi (3,604.05 km) |
| Chapel Hill to Santa Ana (California) | 2,193.65 mi (3,530.34 km) |
| Chapel Hill to Santa Barbara (California) | 2,283.10 mi (3,674.29 km) |
| Chapel Hill to Santa Clara (California) | 2,361.23 mi (3,800.03 km) |
| Chapel Hill to Santa Clara (Oregon) | 2,370.82 mi (3,815.46 km) |
| Chapel Hill to Santa Clarita (California) | 2,215.73 mi (3,565.87 km) |
| Chapel Hill to Santa Cruz (California) | 2,370.01 mi (3,814.16 km) |
| Chapel Hill to Santa Fe (New Mexico) | 1,505.24 mi (2,422.45 km) |
| Chapel Hill to Santa Fe (Texas) | 1,035.94 mi (1,667.18 km) |
| Chapel Hill to Santa Fe Springs (California) | 2,200.14 mi (3,540.79 km) |
| Chapel Hill to Santa Maria (California) | 2,314.33 mi (3,724.55 km) |
| Chapel Hill to Santa Monica (California) | 2,221.71 mi (3,575.50 km) |
| Chapel Hill to Santa Paula (California) | 2,248.25 mi (3,618.20 km) |
