| Chapel Hill to Odessa (Texas) | 1,361.94 mi (2,191.84 km) |
| Chapel Hill to Ogden (Utah) | 1,804.66 mi (2,904.31 km) |
| Chapel Hill to Oildale (California) | 2,228.79 mi (3,586.89 km) |
| Chapel Hill to Ojus (Florida) | 692.10 mi (1,113.82 km) |
| Chapel Hill to Okemos (Michigan) | 549.16 mi (883.79 km) |
| Chapel Hill to Oklahoma City (Oklahoma) | 1,035.57 mi (1,666.59 km) |
| Chapel Hill to Okmulgee (Oklahoma) | 950.26 mi (1,529.30 km) |
| Chapel Hill to Olathe (Kansas) | 888.65 mi (1,430.14 km) |
| Chapel Hill to Old Jamestown (Missouri) | 648.84 mi (1,044.20 km) |
| Chapel Hill to Oldsmar (Florida) | 584.19 mi (940.16 km) |
| Chapel Hill to Olean (New York) | 426.50 mi (686.38 km) |
| Chapel Hill to Olive Branch (Mississippi) | 611.69 mi (984.42 km) |
| Chapel Hill to Olivehurst (California) | 2,319.47 mi (3,732.82 km) |
| Chapel Hill to Olney (Maryland) | 247.17 mi (397.78 km) |
| Chapel Hill to Olympia (Washington) | 2,361.27 mi (3,800.10 km) |
