| Champaign to Superior (Colorado) | 892.13 mi (1,435.75 km) |
| Champaign to Superior (Wisconsin) | 493.03 mi (793.46 km) |
| Champaign to Surprise (Arizona) | 1,402.70 mi (2,257.42 km) |
| Champaign to Susanville (California) | 1,695.47 mi (2,728.60 km) |
| Champaign to Sussex (Wisconsin) | 208.71 mi (335.88 km) |
| Champaign to Suwanee (Georgia) | 478.63 mi (770.29 km) |
| Champaign to Swansea (Illinois) | 141.56 mi (227.82 km) |
| Champaign to Sweetwater (Florida) | 1,090.05 mi (1,754.26 km) |
| Champaign to Sweetwater (Texas) | 856.38 mi (1,378.21 km) |
| Champaign to Sycamore (Illinois) | 131.73 mi (212.00 km) |
| Champaign to Sylacauga (Alabama) | 492.03 mi (791.84 km) |
| Champaign to Sylvania (Ohio) | 262.56 mi (422.54 km) |
| Champaign to Syosset (New York) | 777.08 mi (1,250.60 km) |
| Champaign to Syracuse (New York) | 658.04 mi (1,059.01 km) |
| Champaign to Syracuse (Utah) | 1,246.28 mi (2,005.70 km) |
