| Champaign to Storm Lake (Iowa) | 398.99 mi (642.11 km) |
| Champaign to Storrs (Connecticut) | 842.87 mi (1,356.47 km) |
| Champaign to Stoughton (Wisconsin) | 200.22 mi (322.23 km) |
| Champaign to Stow (Ohio) | 365.88 mi (588.83 km) |
| Champaign to Streamwood (Illinois) | 131.83 mi (212.17 km) |
| Champaign to Streator (Illinois) | 75.65 mi (121.75 km) |
| Champaign to Streetsboro (Ohio) | 371.16 mi (597.32 km) |
| Champaign to Strongsville (Ohio) | 347.32 mi (558.96 km) |
| Champaign to Stuart (Florida) | 1,003.85 mi (1,615.53 km) |
| Champaign to Stuarts Draft (Virginia) | 516.02 mi (830.45 km) |
| Champaign to Sturgis (Michigan) | 189.06 mi (304.26 km) |
| Champaign to Suamico (Wisconsin) | 312.56 mi (503.02 km) |
| Champaign to Sudley (Virginia) | 581.88 mi (936.45 km) |
| Champaign to Suffern (New York) | 743.58 mi (1,196.67 km) |
| Champaign to Suffolk (Virginia) | 672.10 mi (1,081.64 km) |
