| Champaign to Silver Firs (Washington) | 1,750.95 mi (2,817.88 km) |
| Champaign to Silver Spring (Maryland) | 603.92 mi (971.92 km) |
| Champaign to Silver Springs Shores (Florida) | 838.74 mi (1,349.82 km) |
| Champaign to Silverdale (Washington) | 1,774.50 mi (2,855.78 km) |
| Champaign to Silverton (Oregon) | 1,774.37 mi (2,855.58 km) |
| Champaign to Simi Valley (California) | 1,716.31 mi (2,762.14 km) |
| Champaign to Simpsonville (South Carolina) | 497.20 mi (800.16 km) |
| Champaign to Sioux City (Iowa) | 452.03 mi (727.47 km) |
| Champaign to Sioux Falls (South Dakota) | 495.25 mi (797.03 km) |
| Champaign to Skokie (Illinois) | 135.66 mi (218.33 km) |
| Champaign to Sleepy Hollow (New York) | 757.62 mi (1,219.27 km) |
| Champaign to Slidell (Louisiana) | 684.17 mi (1,101.06 km) |
| Champaign to Smithfield (North Carolina) | 627.52 mi (1,009.89 km) |
| Champaign to Smithfield (Utah) | 1,230.50 mi (1,980.29 km) |
| Champaign to Smithville (Missouri) | 338.33 mi (544.49 km) |
