| Champaign to Seymour (Tennessee) | 381.82 mi (614.48 km) |
| Champaign to Shady Hills (Florida) | 872.15 mi (1,403.59 km) |
| Champaign to Shafter (California) | 1,709.68 mi (2,751.46 km) |
| Champaign to Shaker Heights (Ohio) | 363.95 mi (585.73 km) |
| Champaign to Shakopee (Minnesota) | 417.03 mi (671.14 km) |
| Champaign to Sharon (Pennsylvania) | 414.50 mi (667.08 km) |
| Champaign to Sharonville (Ohio) | 213.42 mi (343.46 km) |
| Champaign to Shasta Lake (California) | 1,783.60 mi (2,870.43 km) |
| Champaign to Shawnee (Kansas) | 356.11 mi (573.11 km) |
| Champaign to Shawnee (Oklahoma) | 577.26 mi (929.00 km) |
| Champaign to Sheboygan (Wisconsin) | 252.08 mi (405.69 km) |
| Champaign to Shelby (North Carolina) | 496.09 mi (798.37 km) |
| Champaign to Shelbyville (Indiana) | 138.27 mi (222.53 km) |
| Champaign to Shelbyville (Kentucky) | 209.67 mi (337.44 km) |
| Champaign to Shelbyville (Tennessee) | 334.03 mi (537.57 km) |
