| Champaign to Santa Rosa (California) | 1,833.66 mi (2,950.99 km) |
| Champaign to Santaquin (Utah) | 1,240.52 mi (1,996.42 km) |
| Champaign to Santee (California) | 1,663.55 mi (2,677.23 km) |
| Champaign to Sapulpa (Oklahoma) | 511.27 mi (822.82 km) |
| Champaign to Saraland (Alabama) | 640.31 mi (1,030.48 km) |
| Champaign to Sarasota (Florida) | 941.55 mi (1,515.28 km) |
| Champaign to Sarasota Springs (Florida) | 944.88 mi (1,520.64 km) |
| Champaign to Saratoga (California) | 1,819.86 mi (2,928.78 km) |
| Champaign to Saratoga Springs (New York) | 775.27 mi (1,247.67 km) |
| Champaign to Saratoga Springs (Utah) | 1,243.48 mi (2,001.19 km) |
| Champaign to Sartell (Minnesota) | 484.83 mi (780.26 km) |
| Champaign to Satellite Beach (Florida) | 933.18 mi (1,501.81 km) |
| Champaign to Sauk Rapids (Minnesota) | 481.65 mi (775.14 km) |
| Champaign to Sault Ste. Marie (Michigan) | 481.55 mi (774.99 km) |
| Champaign to Savage (Minnesota) | 412.31 mi (663.55 km) |
