| Champaign to Oswego (Illinois) | 108.47 mi (174.57 km) |
| Champaign to Oswego (New York) | 648.20 mi (1,043.18 km) |
| Champaign to Otsego (Minnesota) | 447.47 mi (720.13 km) |
| Champaign to Ottawa (Illinois) | 90.51 mi (145.66 km) |
| Champaign to Ottawa (Kansas) | 387.69 mi (623.93 km) |
| Champaign to Ottumwa (Iowa) | 226.34 mi (364.26 km) |
| Champaign to Overland (Missouri) | 148.67 mi (239.26 km) |
| Champaign to Overland Park (Kansas) | 352.18 mi (566.78 km) |
| Champaign to Overlea (Maryland) | 626.29 mi (1,007.92 km) |
| Champaign to Oviedo (Florida) | 887.94 mi (1,429.00 km) |
| Champaign to Owasso (Oklahoma) | 487.86 mi (785.13 km) |
| Champaign to Owatonna (Minnesota) | 374.15 mi (602.13 km) |
| Champaign to Owensboro (Kentucky) | 174.29 mi (280.49 km) |
| Champaign to Owings Mills (Maryland) | 611.35 mi (983.88 km) |
| Champaign to Owosso (Michigan) | 290.65 mi (467.76 km) |
