| Champaign to Eau Claire (Wisconsin) | 364.14 mi (586.03 km) |
| Champaign to Echelon (New Jersey) | 702.57 mi (1,130.67 km) |
| Champaign to Eden (North Carolina) | 525.27 mi (845.34 km) |
| Champaign to Eden Prairie (Minnesota) | 420.33 mi (676.46 km) |
| Champaign to Edgewater (Florida) | 875.67 mi (1,409.26 km) |
| Champaign to Edgewater (New Jersey) | 752.40 mi (1,210.87 km) |
| Champaign to Edgewood (Maryland) | 637.43 mi (1,025.84 km) |
| Champaign to Edgewood (Washington) | 1,753.77 mi (2,822.42 km) |
| Champaign to Edina (Minnesota) | 419.43 mi (675.01 km) |
| Champaign to Edinburg (Texas) | 1,109.56 mi (1,785.66 km) |
| Champaign to Edmond (Oklahoma) | 585.05 mi (941.55 km) |
| Champaign to Edmonds (Washington) | 1,760.04 mi (2,832.51 km) |
| Champaign to Edwards (Colorado) | 971.71 mi (1,563.81 km) |
| Champaign to Edwardsville (Illinois) | 129.23 mi (207.98 km) |
| Champaign to Effingham (Illinois) | 70.23 mi (113.02 km) |
