| Champaign to Desert Hot Springs (California) | 1,608.64 mi (2,588.85 km) |
| Champaign to DeSoto (Texas) | 705.01 mi (1,134.60 km) |
| Champaign to Destin (Florida) | 679.15 mi (1,092.99 km) |
| Champaign to Destrehan (Louisiana) | 711.28 mi (1,144.69 km) |
| Champaign to Detroit (Michigan) | 310.96 mi (500.44 km) |
| Champaign to Diamond Bar (California) | 1,674.36 mi (2,694.62 km) |
| Champaign to Diamond Springs (California) | 1,731.67 mi (2,786.85 km) |
| Champaign to Dickinson (North Dakota) | 863.19 mi (1,389.17 km) |
| Champaign to Dickinson (Texas) | 830.40 mi (1,336.41 km) |
| Champaign to Dickson (Tennessee) | 284.17 mi (457.33 km) |
| Champaign to Difficult Run (Virginia) | 588.08 mi (946.43 km) |
| Champaign to Dinuba (California) | 1,696.11 mi (2,729.62 km) |
| Champaign to Discovery Bay (California) | 1,785.18 mi (2,872.97 km) |
| Champaign to Dix Hills (New York) | 785.70 mi (1,264.47 km) |
| Champaign to Dixon (California) | 1,787.44 mi (2,876.61 km) |
