| Centereach to Southern Pines (North Carolina) | 521.37 mi (839.06 km) |
| Centereach to Southfield (Michigan) | 536.58 mi (863.54 km) |
| Centereach to Southgate (Michigan) | 531.33 mi (855.09 km) |
| Centereach to Southlake (Texas) | 1,431.73 mi (2,304.15 km) |
| Centereach to Spanaway (Washington) | 2,448.71 mi (3,940.82 km) |
| Centereach to Spanish Fork (Utah) | 2,010.27 mi (3,235.22 km) |
| Centereach to Spanish Lake (Missouri) | 918.47 mi (1,478.13 km) |
| Centereach to Spanish Springs (Nevada) | 2,428.32 mi (3,908.00 km) |
| Centereach to Sparks (Nevada) | 2,432.41 mi (3,914.59 km) |
| Centereach to Spartanburg (South Carolina) | 631.80 mi (1,016.79 km) |
| Centereach to Spearfish (South Dakota) | 1,571.50 mi (2,529.08 km) |
| Centereach to Speedway (Indiana) | 696.76 mi (1,121.33 km) |
| Centereach to Spencer (Iowa) | 1,140.65 mi (1,835.69 km) |
| Centereach to Spokane (Washington) | 2,212.36 mi (3,560.45 km) |
| Centereach to Spokane Valley (Washington) | 2,203.18 mi (3,545.68 km) |
