| Atlanta (Georgia) to Kirksville | 632.09 mi (1,017.26 km) |
| Denver (Colorado) to Kirksville | 651.42 mi (1,048.35 km) |
| Houston (Texas) to Kirksville | 736.74 mi (1,185.66 km) |
| Washington (District of Columbia) to Kirksville | 832.61 mi (1,339.96 km) |
| Baltimore (Maryland) to Kirksville | 848.94 mi (1,366.24 km) |
| Philadelphia (Pennsylvania) to Kirksville | 920.36 mi (1,481.17 km) |
| Brooklyn (New York) to Kirksville | 978.34 mi (1,574.48 km) |
| New York (New York) to Kirksville | 979.41 mi (1,576.20 km) |
| Queens (New York) to Kirksville | 985.79 mi (1,586.47 km) |
| Tampa (Florida) to Kirksville | 1,021.61 mi (1,644.12 km) |
| Boston (Massachusetts) to Kirksville | 1,122.72 mi (1,806.84 km) |
| Phoenix (Arizona) to Kirksville | 1,168.34 mi (1,880.26 km) |
| Miami (Florida) to Kirksville | 1,224.20 mi (1,970.16 km) |
| Las Vegas (Nevada) to Kirksville | 1,258.13 mi (2,024.76 km) |
| Riverside (California) to Kirksville | 1,429.55 mi (2,300.65 km) |
| San Diego (California) to Kirksville | 1,449.21 mi (2,332.28 km) |
| Los Angeles (California) to Kirksville | 1,477.26 mi (2,377.43 km) |
| Seattle (Washington) to Kirksville | 1,555.75 mi (2,503.73 km) |
| Portland (Oregon) to Kirksville | 1,557.13 mi (2,505.95 km) |
| San Francisco (California) to Kirksville | 1,605.62 mi (2,584.00 km) |
| St. Louis (Missouri) to Kirksville | 164.69 mi (265.05 km) |
| Chicago (Illinois) to Kirksville | 278.82 mi (448.71 km) |
| Minneapolis (Minnesota) to Kirksville | 331.10 mi (532.85 km) |
| Detroit (Michigan) to Kirksville | 514.09 mi (827.36 km) |
| Dallas (Texas) to Kirksville | 561.94 mi (904.35 km) |
