| Miami (Florida) to Caguas | 1,045.94 mi (1,683.28 km) |
| Tampa (Florida) to Caguas | 1,239.63 mi (1,994.98 km) |
| Atlanta (Georgia) to Caguas | 1,561.70 mi (2,513.32 km) |
| Washington (District of Columbia) to Caguas | 1,573.04 mi (2,531.56 km) |
| Baltimore (Maryland) to Caguas | 1,587.80 mi (2,555.31 km) |
| Philadelphia (Pennsylvania) to Caguas | 1,599.34 mi (2,573.88 km) |
| Brooklyn (New York) to Caguas | 1,618.65 mi (2,604.97 km) |
| New York (New York) to Caguas | 1,621.11 mi (2,608.93 km) |
| Queens (New York) to Caguas | 1,622.57 mi (2,611.28 km) |
| Boston (Massachusetts) to Caguas | 1,690.45 mi (2,720.52 km) |
| Detroit (Michigan) to Caguas | 1,946.08 mi (3,131.92 km) |
| Houston (Texas) to Caguas | 2,009.33 mi (3,233.70 km) |
| St. Louis (Missouri) to Caguas | 2,024.79 mi (3,258.59 km) |
| Chicago (Illinois) to Caguas | 2,069.73 mi (3,330.90 km) |
| Dallas (Texas) to Caguas | 2,152.52 mi (3,464.15 km) |
| Minneapolis (Minnesota) to Caguas | 2,421.72 mi (3,897.38 km) |
| Denver (Colorado) to Caguas | 2,746.59 mi (4,420.21 km) |
| Phoenix (Arizona) to Caguas | 3,023.57 mi (4,865.97 km) |
| Las Vegas (Nevada) to Caguas | 3,229.71 mi (5,197.71 km) |
| San Diego (California) to Caguas | 3,306.65 mi (5,321.54 km) |
| Riverside (California) to Caguas | 3,329.12 mi (5,357.70 km) |
| Los Angeles (California) to Caguas | 3,387.93 mi (5,452.35 km) |
| San Francisco (California) to Caguas | 3,635.88 mi (5,851.38 km) |
| Portland (Oregon) to Caguas | 3,723.09 mi (5,991.73 km) |
| Seattle (Washington) to Caguas | 3,737.54 mi (6,015.00 km) |
