| Cartagena to Southern Pines (North Carolina) | 4,229.24 mi (6,806.30 km) |
| Cartagena to Southfield (Michigan) | 4,188.73 mi (6,741.10 km) |
| Cartagena to Southgate (Michigan) | 4,194.37 mi (6,750.19 km) |
| Cartagena to Southlake (Texas) | 5,175.24 mi (8,328.74 km) |
| Cartagena to Spanaway (Washington) | 5,559.78 mi (8,947.60 km) |
| Cartagena to Spanish Fork (Utah) | 5,504.68 mi (8,858.93 km) |
| Cartagena to Spanish Lake (Missouri) | 4,629.96 mi (7,451.19 km) |
| Cartagena to Spanish Springs (Nevada) | 5,835.45 mi (9,391.26 km) |
| Cartagena to Sparks (Nevada) | 5,841.31 mi (9,400.67 km) |
| Cartagena to Spartanburg (South Carolina) | 4,363.00 mi (7,021.58 km) |
| Cartagena to Spearfish (South Dakota) | 5,003.69 mi (8,052.67 km) |
| Cartagena to Speedway (Indiana) | 4,411.50 mi (7,099.62 km) |
| Cartagena to Spencer (Iowa) | 4,695.76 mi (7,557.10 km) |
| Cartagena to Spokane (Washington) | 5,367.12 mi (8,637.55 km) |
| Cartagena to Spokane Valley (Washington) | 5,360.63 mi (8,627.10 km) |
