| Calexico to Superior (Colorado) | 761.94 mi (1,226.22 km) |
| Calexico to Superior (Wisconsin) | 1,566.45 mi (2,520.96 km) |
| Calexico to Surprise (Arizona) | 188.94 mi (304.07 km) |
| Calexico to Susanville (California) | 605.02 mi (973.68 km) |
| Calexico to Sussex (Wisconsin) | 1,642.63 mi (2,643.56 km) |
| Calexico to Suwanee (Georgia) | 1,808.74 mi (2,910.88 km) |
| Calexico to Swansea (Illinois) | 1,483.52 mi (2,387.50 km) |
| Calexico to Sweetwater (Florida) | 2,160.17 mi (3,476.45 km) |
| Calexico to Sweetwater (Texas) | 877.69 mi (1,412.50 km) |
| Calexico to Sycamore (Illinois) | 1,598.53 mi (2,572.59 km) |
| Calexico to Sylacauga (Alabama) | 1,690.12 mi (2,719.98 km) |
| Calexico to Sylvania (Ohio) | 1,844.62 mi (2,968.63 km) |
| Calexico to Syosset (New York) | 2,367.83 mi (3,810.65 km) |
| Calexico to Syracuse (New York) | 2,239.23 mi (3,603.69 km) |
| Calexico to Syracuse (Utah) | 610.38 mi (982.32 km) |
