| Calexico to Scottsboro (Alabama) | 1,692.69 mi (2,724.12 km) |
| Calexico to Scottsdale (Arizona) | 220.98 mi (355.63 km) |
| Calexico to Scranton (Pennsylvania) | 2,256.10 mi (3,630.85 km) |
| Calexico to Seabrook (Maryland) | 2,191.02 mi (3,526.10 km) |
| Calexico to Seabrook (Texas) | 1,227.62 mi (1,975.67 km) |
| Calexico to Seaford (New York) | 2,368.35 mi (3,811.50 km) |
| Calexico to Seagoville (Texas) | 1,100.65 mi (1,771.32 km) |
| Calexico to Seal Beach (California) | 166.26 mi (267.58 km) |
| Calexico to Searcy (Arkansas) | 1,369.64 mi (2,204.22 km) |
| Calexico to Seaside (California) | 450.67 mi (725.28 km) |
| Calexico to SeaTac (Washington) | 1,080.32 mi (1,738.61 km) |
| Calexico to Seattle (Washington) | 1,092.12 mi (1,757.59 km) |
| Calexico to Sebastian (Florida) | 2,107.71 mi (3,392.03 km) |
| Calexico to Sebring (Florida) | 2,057.83 mi (3,311.75 km) |
| Calexico to Secaucus (New Jersey) | 2,338.32 mi (3,763.17 km) |
